HPLC/MS/MS
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Description
LC/MS/MS is a powerful and widely used tool in qualitative and quantitative residue and contaminant analysis. The mixture is separated with HPLC preferably using a reversed-phase column. The analytes can be ionized with a suitable ion source by various methods, followed by partial fragmentation. After acceleration, they are deflected by a magnetic field which resolves them according to their mass.
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Specifications
• Ion source : ESI, APCI
• Mass range : 50 ~ 3,000 (m/z)
• Resolution : 0.6 unit
• Accuracy : 0.1 ~ 0.3 % absolute
• Scan speed : 26,000 amu/sec
• Mass accuracy : ± 0.15 unit
• Electro sensitivity
- MS : reserpine 5 pg S/N 10 : 1
- MS/MS : reserpine 1 pg S/N 50 : 1
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Applications
• Analysis of organic composition
• Identification of molecular weight
• Analysis of DNA, RNA, proteins
• Analysis of environmental samples (water, waste, soil)