Matrix-assisted laser desorption/ionization (MALDI) is a soft ionization technique used in mass spectrometry, allowing the analysis of biomolecules and large organic, which tend to be fragile and fragment when ionized by more conventional ionization methods.

The type of a mass spectrometer most widely used with MALDI is the TOF (time-of-flight mass spectrometer), mainly due to its large mass range. The TOF measurement procedure is also ideally suited to the MALDI ionization process since the pulsed laser takes individual ‘shots’ rather than working in continuous operation. MALDI-TOF instrument or reflectron is equipped with an “ion mirror” that reflects ions using an electric field, thereby doubling the ion flight path and increasing the resolution.

– Topic: Introduction and training of MALDI-TOF/TOF

– Date & time: 2019. 04. 29. (Mon.) a.m. 09:30

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